Premium
A Novel Method to Evaluate Thromboresistance of Drip Chambers with Filter Used in Extracorporeal Blood Circuits for Hemodialysis
Author(s) -
Yamazaki Manabu,
Kobayashi Kenyu,
Mori Yuichi,
Satoh Tadaaki,
Kubota Sunao
Publication year - 1997
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1111/j.1525-1594.1997.tb00354.x
Subject(s) - extracorporeal , peristaltic pump , blood flow , biomedical engineering , femoral artery , femoral vein , filter (signal processing) , vein , medicine , materials science , surgery , computer science , radiology , engineering , mechanical engineering , computer vision
We have developed a novel method to simultaneously evaluate thromboresistance of two different types of drip chambers with a filter used in extracorporeal blood circuits for hemodialysis using canine arteriovenous shunt models. Bilateral bypasses between the femoral artery and vein on both sides of the animal were formed with 2 test circuits consisting of polyvinyl chloride tubing and two types of drip chambers with filters. Blood flow was derived into the drip chambers with a filter and returned to the femoral vein without using peristaltic pumps and systemic anticoagulants. By monitoring the quantitative changes of the blood flow rate through each drip chamber with a filter and measuring the time elapsed before the blood flow through its was completely obstructed by clots, thromboresistance of the drip chambers was evaluated under the same blood conditions. The drip chamber with a filter that had a small effective filter area, a big pore size, and slitlike pores showed better thromboresistance. This novel method proved useful in evaluating the thromboresistance of differently designed drip chambers with a filter.