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Blood Density Monitoring During Dialysis
Author(s) -
Yamauchi Tatsuyuki,
Yanai Mitsuru,
Takahashi Susumu,
Man NguyenKhoa
Publication year - 1996
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1111/j.1525-1594.1996.tb04584.x
Subject(s) - hemodialysis , ultrafiltration (renal) , dialysis , medicine , anesthesia , blood volume , cardiology , urology , chemistry , chromatography
Continuous monitoring of blood density (BD) was preformed in 4 stable dialysis patients in 20 sessions using a density meter based on a mechanical oscillator technique. Mean predialysis and postdialysis BDs were 1.0427 ± 0.0031 g/cm 3 and 1.0502 ± 0.0055 g/cm respectively. For similar predialysis to postdialysis total body water reduction, significant difference in the mean BD increase was found between hypotensive and nonhy‐potensive groups (1.29 ± 0.07%, 0.47 ± 0.12%, respectively; p < 0.001). Eight hypotensive episodes occurred during 6 sessions. The mean value of the blood density changes slope (dBD/dt) during the 5 min preceding a hypotensive episode increased about 2.5 times more than did the mean of the predialysis to postdialysis blood density slope (27.6 ± 2.2 g/cm 3 min 10 ‐5 , 10.5 ± 0.4 g/cm 3 min 10 ‐5 respectively; p < 0.001) under the condition of a constant ultrafiltration rate of 18.9 ± 0.6 ml/min. Continuous monitoring of blood density allows abrupt change in plasma volume to be identified and seems to have a potential utility to the prevention of symptomatic hypotension episodes in patients receiving hemodialysis.