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Immunomodulation in Transplantation with Photopheresis
Author(s) -
Barr Mark L.
Publication year - 1996
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1111/j.1525-1594.1996.tb04580.x
Subject(s) - photopheresis , peripheral blood , ultraviolet light , transplantation , medicine , immune system , immunology , peripheral blood mononuclear cell , chemistry , surgery , lymphoma , photochemistry , biochemistry , in vitro
Photopheresis is a technique in which peripheral blood mononuclear cells, in the presence of a photoacti‐vatable compound, are exposed extracorporeally to ultraviolet A light and reinfused, inducing a host autoregula‐tory immune response. Experimental work and ongoing clinical studies are helping to define the role of this novel, safe, and non‐toxic immunomodulating technology in the field of transplantation.