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Clinical Use of Centrifugal Pumps and the Roller Pump in Open Heart Surgery: A Comparative Evaluation
Author(s) -
Yoshikai Masaru,
Hamada Masakatsu,
Takarabe Kyoumi,
Okazaki Yukio,
Yoshika Masaru
Publication year - 1996
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1111/j.1525-1594.1996.tb04507.x
Subject(s) - centrifugal pump , antithrombin , coagulation , lactate dehydrogenase , cardiopulmonary bypass , rotodynamic pump , peristaltic pump , surgery , medicine , cardiology , chemistry , impeller , heparin , engineering , mechanical engineering , variable displacement pump , reciprocating pump , biochemistry , progressive cavity pump , enzyme
Centrifugal pumps have been used widely as the main pump in open heart surgery to reduce damage to blood elements and to reduce the activation of the coagulation system. The purpose of this study was the evaluation and comparison of the effects of two types of centrifugal pumps and of one type of roller pump on blood elements, the coagulation system, complements, and immunoglobulins. Two types of centrifugal pumps (Lifestream; St. Jude Medical, Chelmsford, Massachusetts; and BP‐80; Medtronic, BioMedicus, Inc., Eden Prairie, Minnesota, U.S.A.) and one roller pump (Mera Co.) were used separately as the main pump for cardio‐pulmonary bypass (CPB) in 29 patients. Platelet counts, lactate dehydrogenase, antithrombin III, thrombin‐antithrombin complex (TAT), complements (C3, C4, and CH50) and immunoglobulins G, A, and M values were measured before and after CPB and compared. Values, except those for TAT, showed no significant difference among the three groups. The TAT values increased less in each of the centrifugal pump groups than in the roller pump group. This finding suggests that thrombin synthesis might be suppressed by the use of a centrifugal pump.