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Numerical Simulation of Nonpulsatile Left Ventricular Bypass
Author(s) -
Mitsui Norimasa,
Fukunaga Shintaro,
Koura Yoshihiko,
Morita Satoru,
Hotei Hiroshi,
Sueshiro Masafumi,
Sueda Taijiro,
Matsuura Yuichiro
Publication year - 1996
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1111/j.1525-1594.1996.tb04494.x
Subject(s) - ventricle , hemodynamics , ventricular assist device , cardiology , compliance (psychology) , medicine , circulatory system , pulsatility index , blood flow , cardiac output , blood pressure , cardiac index , heart failure , biology , genetics , psychology , social psychology , fetus , pregnancy
A computer simulation was carried out to investigate the influence of nonpulsatile left ventricular assistance on hemodynamics. A simulation circuit was constructed to represent the circulatory system. A source of current was added to denote the nonpulsatile blood pump. The left and right ventricles were replaced by variable compliances. Left heart failure was simulated by decreasing the amount of compliance change of the left ventricle. We introduced a pulsatility indicator (PI) to clarify the pulsatility characteristics in the hemodynamics; this PI was defined as the ratio of the pulse pressure (PP) to the mean aortic pressure (AoP). When nonpulsatile bypass flow increased, the mean AoP, tension time index (TTI), and diastolic pressure time index (DPTI) increased, and cardiac output, PP, and PI decreased. When assisted flow increased with the constant total flow rate, the mean AoP and DPTI changed little; the PP, TTI, and PI decreased, and the endocardial viability rate increased. The PI would be helpful in evaluating the effect of pulsatility.