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Hemolysis and Heat Generation in Six Different Types of Centrifugal Blood Pumps
Author(s) -
Araki Kenji,
Taenaka Yoshiyuki,
Masuzawa Toru,
Tatsumi Eisuke,
Wakisaka Yoshinari,
Watari Masanobu,
Nakatani Takeshi,
Akagi Haruhiko,
Baba Yuzo,
Anai Hirofumi,
Park Young Hwan,
Eya Kazuhiro,
Toda Koichi,
Takano Hisateru
Publication year - 1995
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1111/j.1525-1594.1995.tb02453.x
Subject(s) - hemolysis , centrifugal pump , nuclear engineering , medicine , environmental science , engineering , mechanical engineering , impeller
What the most causative factor affecting hemolysis is still controversial. To resolve this problem, we investigated the relationship between hemolysis and heat generation in six types of centrifugal blood pumps (Bio–Pump, Delphin, Capiox, Nikkiso, Isoflow, and Toyobo). The analyzed parameters were index of hemolysis in fresh goat blood, pumping performance, and heat generation in a thermally isolated mock circuit. These parameters were analyzed at a flow rate of 5 L/min by changing the pressure head (100 mm Hg and 500 mm Hg). At 500 mm Hg of pressure head, the Bio–Pump needed the highest rotation number and showed the highest hemolytic rate and heat generation. The index of hemolysis is well correlated to heat generation (r 2 = 0. 721). Heat may originate from the motor by conduction, hydraulic energy loss, and mechanical friction between the shaft and seal. We strongly suspect that hemolysis was caused by a factor such as mechanical friction which generates heat locally.