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A Compact Centrifugal Pump for Cardiopulmonary Bypass
Author(s) -
Sasaki Tatsuya,
Jikuya Tomoaki,
Aizawa Takeshi,
Shiono Motomi,
Sakuma Ichiro,
Takatani Setsuo,
Glueck Julia,
Noon George P.,
Nosé Yukihiko,
DeBakey Michael E.
Publication year - 1992
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1111/j.1525-1594.1992.tb00557.x
Subject(s) - centrifugal pump , impeller , cardiopulmonary bypass , peristaltic pump , hemolysis , thrombus , heart lung machine , materials science , biomedical engineering , seal (emblem) , mechanical engineering , medicine , surgery , cardiology , engineering , art , visual arts
A majority of the cardiopulmonary bypass (CPB) systems still utilize bulky roller pumps. A direct‐drive small centrifugal pump intended for second‐generation CPB pump has been developed. The pump has a 50 mm diameter impeller and provides a 6 L/min flow at 3,000 rpm against 300 mm Hg. A flexible drive shaft allows us to separate the pump head from the console resulting in easier manipulation. An in vitro study showed that the pump generated less hemolysis (index of hemolysis = 0.0011, comparable to the value for Bio‐medicus BP‐80). To improve blood flow around the shaft‐seal region and to reduce thrombus formation around the shaft, six holes were drilled through the impeller. In biventricular bypass experiments using calves, our pump demonstrated excellent antithrombogenicity and durability for 48 h. And the compact and atraumatic centrifugal pump system showed excellent performance and easy manipulation under acfual CPB conditions in animal.