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Gas‐Exchange Function of a Preprimed Pediatric Oxygenator Stored for One Year for Emergency Cardiopulmonary Bypass
Author(s) -
Otsu Tetsuro,
Terasaki Hidenori,
Choi Hyun,
Tajiri Akihiko,
Okamoto Taisuke,
Matsuyama Kumi,
Morioka Tohru
Publication year - 1992
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1111/j.1525-1594.1992.tb00331.x
Subject(s) - oxygenator , membrane oxygenator , cardiopulmonary bypass , medicine , anesthesia , extracorporeal circulation , blood flow , cardiology
To save priming time and perform more rapid initiation of emergency cardiopulmonary bypass for acute cardiopulmonary failure, an extracorporeal circuit with a hollow‐fiber oxygenator (EL‐2000 for pediatric use; Kurary Co. Ltd., Osaka, Japan) was preprimed, and the gas‐exchange function was evaluated after 1 year of storage. EL‐2000 has a dense polyolefin membrane with a surface area of 0.3 m 2 . When the bypass flow rates were 250, 500, 1,000, and 1,500 ml/min with 100% oxygen at the same flow rate as the bypass blood flow (namely, V/Q = 1) to the oxygenator, oxygen transport rates of the stored oxygenator were 19.6 ‡ 0.3, 38.3 ‡ 0.41, 64.4 ‡ 0.9, and 76.4 ‡ 2.7 ml/min (n = 5, mean ‡ SD), respectively. Pco 2 differences between pre‐ and postoxygenator blood (ΔPco,) were 18.6 ‡ 1.4, 12.0 ‡ 1.6, and 4.4 ‡ 1.2 mm Hg at V/Q = 1 and the same bypass blood flow rates, respectively, excluding 1,500 ml/min, the data for which were excluded because of preparatory failure. Pco, removal indices (defined as the ratio of ΔPco, to Pco 2 in preoxygenator blood) were 0.45 ‡ 0.03, 0.29 ‡ 0.12, and 0.10 ‡ 0.03, respectively. Though the evaluation was done using only a single oxygenator, we feel strongly that the gas‐exchange function of the preprimed dense‐membrane hollow‐fiber oxygenator will be preserved even after 1 year of storage.