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Development of a Flow‐Transformed Pulsatile Total Artificial Heart for Total Implantation
Author(s) -
Imachi Kou,
Chinzei Tsuneo,
Abe Yuusuke,
Mabmchi Kunihiko,
Imanishi Kaoru,
Yonezawa Takumi,
Suzuki Akira,
Isoyama Takashi,
Atsumi Kazuhiko,
Fujimasa Iwao
Publication year - 1992
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1111/j.1525-1594.1992.tb00318.x
Subject(s) - pulsatile flow , artificial heart , solenoid , backflow , aorta , biomedical engineering , cardiology , medicine , inlet , engineering , mechanical engineering
To realize a totally implantable total artificial heart (TAH), a new pulsatile TAH, the flow‐transformed pulsatile TAH (FTPTAH), was developed. The system was composed of a single centrifugal pump (CFP) and two three‐way valves. One port of each three‐way valve was connected to the inlet and outlet of a CFP. The other two ports of each valve were connected to the right and left atrium, and the pulmonary artery and aorta. The CFP can perfuse the pulmonary and systemic circulation alternately with pulsatile flow by switching the two three‐way valves. A prototype and the secondary model in which the solenoid valves and a spool valve were included, respectively, were connected to a mock circulatory unit with the results that a pulsatile TAH with physiological flow wave form could be obtained from a single CFP, about 5 Llmin of pulsatile output could be obtained alternately on the right and left side by switching the solenoid valves or a spool valve, and flow balance between the right and left could be easily controlled by the switching duration. The system is feasible for a totally implantable TAH because it does not need a compliance chamber and can be miniaturized.