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Techniques for Optimization of Pulsatile Ventricular Assist Device Support
Author(s) -
Mills Timothy C.,
Ott Richard A.
Publication year - 1992
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1111/j.1525-1594.1992.tb00299.x
Subject(s) - pulsatile flow , computer science , biomedical engineering , cardiology , medicine , intensive care medicine
For some time now researchers have argued the efficacy of pulsatile versus nonpulsatile hemodynamic support. Pulsatile systems, while providing a more physiological pumping source, are burdened with a multipa‐rametric output function that can greatly affect the utility of such ventricular assist device (VAD) support. A simplified approach to the optimization of the pulsatile VADs' output function has been developed. This approach yields device outputs of approximately 5.5 Limin at physiologic pressures while demonstrating clinically acceptable blood chemistry. Obtaining this optimal operating point involves the determination of the VAD system output function for a range of fill‐enhancing vacuum settings. A quantitative method for evaluating synchronous versus asynchronous pumping modes as related to coronary perfusion is also demonstrated.