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Effects of Hypertonic Peritoneal Dialysis Solutions on Neutrophil Superoxide Production
Author(s) -
Zhou Fang Q.,
Manahan Ferdinand J.,
Yu Alex W.,
Rahman Mohamed A.,
Nawab Zeenat M.,
Fisher Kenneth A.,
Ing Todd S.
Publication year - 1990
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1111/j.1525-1594.1990.tb02995.x
Subject(s) - superoxide , peritoneal dialysis , tonicity , chemistry , neutrophile , immunology , medicine , microbiology and biotechnology , biochemistry , biology , inflammation , enzyme
. Superoxide produced by neutrophils plays an important role in the killing of bacterial pathogens. The effects of glucose‐containing peritoneal dialysis solutions on superoxide production by canine and human neutrophils were studied. A significant decrement in superoxide generation was noted with the 2.27% and 3.86% glucose solutions. The results suggest that hypertonic peritoneal dialysis solutions curtail neutrophil superoxide generation.