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Quantification of Perivalvular Thrombus Formation in Blood Pumps by Polar Coordinate Mapping
Author(s) -
Pantalos George M.,
Everett Scott D.,
Mohammad S. Fazal,
Burns Gregory L.,
Solen Kenneth A.,
Reynolds Larry O.,
Olsen Don B.
Publication year - 1990
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1111/j.1525-1594.1990.tb02979.x
Subject(s) - thrombus , polar coordinate system , polar , cardiology , medicine , geometry , mathematics , physics , astronomy
A polar coordinate mapping technique (PCMT) to quantitatively describe perivalvular thrombus formation was applied in the examination of prosthetic valves from paracorporeal assist devices. The method begins by photographing the upstream and downstream views of the freshly retrieved valves using Transparency film. The valve images are then projected onto 10 x planforms of the valves, and the boundaries of the observable thrombi are traced. The radial thrombus length is then measured at 5d̀ increments and plotted on Cartesian coordinates as a function of polar coordinate. Mean radial thrombus length and incidence of thrombus are calculated. Statistical analysis can then be used to test for differences in the length, incidence, and pattern of thrombus formation between test groups. The effect of valve selection, anticoagulant regime, and other factors that influence thrombus formation can be quantitatively compared with the PCMT. Consequently, the PCMT could be a valuable assessment tool for efforts being made to reduce thrombosis in prosthetic blood pumps.