Premium
Paracorporeal Assistance System for Restoring Cardiac Activity
Author(s) -
Tolpekin V. E.,
Koblov L. F.,
Kuvaev A. E.,
Gasanov E. K.
Publication year - 1987
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1111/j.1525-1594.1987.tb02622.x
Subject(s) - ventricle , cardiology , hemodynamics , ventricular fibrillation , medicine , ventricular function , perfusion , cardiac function curve , normal sinus rhythm , cardiopulmonary bypass , sinus rhythm , atrial fibrillation , heart failure
Abstract: Two series of experiments were conducted to assess the potential of artificial ventricular bypass in restoring cardiac activity. One series evaluated use of a paracorporeal left ventricle in 17 calves; the other evaluated biventricular bypass in 11 calves. Module pumps with a seamless blood chamber of polyurethane were used. Pump function and system parameters were controlled by a Sinus VK‐2 control system. Assisted perfusion began with the induction of ventricular fibrillation. The experiments showed that left ventricular bypass was an effective method for long‐term maintenance of the hemodynamics during fibrillation, leading to certain biochemical corrections and restored electrical activity and myocardial contractile function. The hemodynamic state was maintained at a higher level with biventricular bypass and was accompanied by a greater percentage of restored myocardial function. Uneven restoration of contractile activity in the left and right ventricles points to the need for adequate support of both ventricles.