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Large‐Surface Hemodialysis
Author(s) -
Rotellar Emilio,
Martinez Esther,
Samso Jose Maria,
Barrios Jose,
Simo Ricardo,
Mulero Juan Francisco,
Perez Maria Dolores,
Bandrés Silvino,
Piñol Juan
Publication year - 1986
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1111/j.1525-1594.1986.tb02586.x
Subject(s) - hemodialysis , creatinine , uric acid , urea , potassium , chemistry , bicarbonate , body surface area , medicine , urology , surgery , biochemistry , organic chemistry
A hemodialysis device with a surface of 5 m 2 , a blood flow ( Q B ) of 500 ml/min, and a dialysate flow ( Q D ) of 1,000 ml/min has enabled the authors to obtain in 6 h/week the same clearances for urea, creatinine, uric acid, phosphates, and vitamin B 12 as has conventional hemodialysis (CH), which takes from 12 to 15 h/week. Twenty‐five patients were hemodialyzed throughout 1 year with CH and another year with large‐surface hemodialysis, 20 with a creatinine clearance ( C Cr ) of 0.5 ml/min and 5 with a C Cr between 0.5 and 4.5 ml/min. All followed a free diet and led a normal life. Hemodialysis time was 6 h/week, and the results obtained were equal to those of the previous year with a CH of 12 h/week. The use of a bicarbonate dialysate rich in glucose, with a relatively high level of potassium and sodium, can avoid the disequilibrium syndrome caused by quick hemodialysis and makes possible the removal of excess liquid in only 6 h/week, without disturbances for the patient.