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Residual Ethylene Oxide in Hollow‐Fiber Dialyzers
Author(s) -
Henne Werner,
Dietrich W.,
Pelger Michael,
Sengbusch Giünter
Publication year - 1984
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1111/j.1525-1594.1984.tb04295.x
Subject(s) - ethylene oxide , materials science , fiber , residual , poly ethylene , ethylene , composite material , chemistry , polymer , computer science , organic chemistry , catalysis , algorithm , copolymer
The deaeration and extraction kinetics of ethylene oxide (ETO) in hollow‐fiber dialyzers were examined. The investigations showed that both deaeration and extraction can be described by two additive first‐order kinetic expressions. The ETO content of membranes decreased rapidly at first, followed by a second slower decrease. Even after prolonged storage time, residual ETO was still detectable in the milligram range. These residuals cannot be eliminated by the usual rinsing of the di‐alyzer prior to use.