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Plasma Exchange for Treatment of Intractable Psoriasis
Author(s) -
Maeda Kenji,
Shinzato Torn,
Naotsuka Masaaki,
Usuda Masatsune,
Sezaki Ryozo,
Niwa Toshimitsu,
Kawaguchi Shunsuke,
Saito Akira,
Yamanaka Naoki,
Ohta Kazuhiro
Publication year - 1983
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1111/j.1525-1594.1983.tb04225.x
Subject(s) - hemoperfusion , psoriasis , medicine , hemofiltration , plasmapheresis , therapeutic plasma exchange , complete remission , dermatology , surgery , chemotherapy , immunology , hemodialysis , antibody
Hemofiltration and plasma exchange, using a plasma separator with membranes, were used in 14 psoriatic patients. The efficacies of the treatments were compared. Among the patients, 13 were treated with hemofiltration and/or direct hemoperfusion, 5 experienced complete remission, 5 improved, and 3 remained unaffected. In these 3 cases, plasma exchange was performed. The first patient, who suffered from psoriasis pustulosa with arthropathica, achieved complete remission with only two treatments of 2‐L plasma exchange. Joint pain was also eliminated. Both skin lesions and joint pain were markedly improved in the second patient, who suffered from psoriasis vulgaris with arthropathica. The third patient showed marked improvement with only two plasma exchanges, and is under continuing observation.