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Concentrations of 5‐Hydroxyindoleacetic Acid and Homovanillic Acid in the Cerebrospinal Fluid of Chronic Therapy‐Resistant Schizophrenics Before and After Hemodialysis Therapy
Author(s) -
Magnusson Olle,
Fowler Christopher J.,
Ross Svante B.,
Schulman Abraham,
Wetterberg Lennart
Publication year - 1983
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1111/j.1525-1594.1983.tb04208.x
Subject(s) - homovanillic acid , cerebrospinal fluid , 5 hydroxyindoleacetic acid , hemodialysis , monoamine neurotransmitter , dialysis , medicine , lumbar puncture , dopamine , chemistry , serotonin , receptor
The concentrations of the monoamine metabolites 5‐hydroxyindoleacetic acid (5‐HIAA) and homovanillic acid (HVA) have been determined by high‐performance liquid chromatography in samples of lumbar cerebrospinal fluid from chronic therapy‐resistant schizophrenics, both before and after either inactive or active hemodialysis for 10 weeks. A reasonable test‐re‐test reliability was found for 5‐HIAA during the inactive dialysis, but this was not found during active dialysis.