Premium
Levomepromazine Elimination in Patients During Active and Sham Hemodialysis
Author(s) -
Andersson S.B.,
Forshell G. Plym,
Schulman A.,
Wetterberg L.,
Asaba H.
Publication year - 1983
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1111/j.1525-1594.1983.tb04207.x
Subject(s) - levomepromazine , hemodialysis , medicine , dialysis , drug , plasma concentration , crossover study , anesthesia , urology , pharmacology , pathology , alternative medicine , haloperidol , dopamine , placebo
The effect of active and sham dialysis on the plasma concentration of levomepromazine was studied in seven schizophrenic patients undergoing hemodialysis treatment in a double‐blind crossover study. Samples of blood were collected before, after 2 h and 5 h of treatment, and once a week during the treatment program. The plasma concentrations decreased during both active and sham dialysis. The data indicate that there was no significant difference in the elimination of the drug between active and sham hemodialysis.