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Increment in Dialysate Sodium with Sodium Chloride or Bicarbonate Addition
Author(s) -
Raja Rasib M.,
Fernandes Michael,
Kramer Mark S.,
Rosenbaum Jerry L.,
Barber Kevin
Publication year - 1983
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1111/j.1525-1594.1983.tb04180.x
Subject(s) - sodium , bicarbonate , sodium bicarbonate , chemistry , hemodialysis , sodium acetate , dialysis , chromatography , medicine , organic chemistry
Hemodialysis was performed in 12 patients for 2 weeks each utilizing acetate dialysate containing 134 mEq/L sodium and dialysate containing 143 mEq/L sodium, achieved by the addition of sodium chloride or sodium bicarbonate to the acetate dialysate. Intradialytic morbidity was lower, dialysis hypoxemia less marked, and predialysis blood pH higher with the bicarbonate‐than with the chloride‐added dialysate. The long‐term use of sodium bicarbonate‐added dialysate in three patients was safe. Dialysate pH adjustment was not required. These findings suggest that the addition of sodium bicarbonate (50–75 g) to acetate dialysate may be preferred to sodium chloride for increasing dialysate sodium in selected patients.