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Experimental and Clinical Ventricular Bypass During Acute Heart Failure
Author(s) -
Lokshin Leonid S.,
Osipov Valentin P.,
Knjazeva Galina,
Rogov Konstantin A.,
Lepilin Mikhail G.,
Arseniev Sergei B.,
Romanov Vladimir A.,
Leonova Svetlana A.
Publication year - 1982
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1111/j.1525-1594.1982.tb01676.x
Subject(s) - cardiogenic shock , cardiology , heart failure , medicine , shock (circulatory) , hemodynamics , left ventricles , cardiopulmonary bypass , myocardial infarction , ventricle
Mechanical support of the failing heart in the form of bypass of the left and right ventricles by roller pumps was used in 25 dogs with model cardiogenic shock. Early application of left ventricular bypass in acute heart failure normalizes the myocardial bioenergy state and promotes reversible changes in myocardial infrastructure as demonstrated by an increased surface area of mitochondrial cristae. On the basis of hemodynamics and morphology, we conclude that pump‐aided bypass of ventricles without synchronization is a simple and effective method of circulation assistance. Mechanical support duration from 1 to 138 hours has been used in 10 patients following corrective heart surgery.