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Controlled Ultrafiltration During Single‐Pass Dialysis with the RP‐6 Dialyzer and Evaluation of Its Time‐Dependent Ultrafiltration Index
Author(s) -
Zelman Allen,
Bulloch Edwin,
Stephen Robert,
Kablitz Carl,
Duffy Douglass,
Kolff Willem J.
Publication year - 1980
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1111/j.1525-1594.1980.tb03931.x
Subject(s) - ultrafiltration (renal) , concentration polarization , chemistry , chromatography , dialysis , urology , analytical chemistry (journal) , membrane , surgery , medicine , biochemistry
A simple and inexpensive method is described for controlling ultrafiltration when using the high flux RP‐6 dialyzer. When the RP‐6 is operated in the co‐current mode and with single‐pass dialysate delivery, (P bo ‐P dn ) can be used to accurately and safely control ultrafiltration. Combined results from ten dialyses indicate there is a pressure‐dependent concentration polarization which affects ultrafiltration as reported previously, and in addition, a time‐dependent effect indicating a more complex dialyzer/blood interaction. The ultrafiltration index decreases linearly with time. The ultrafiltration can be adequately predicted by Q v =16.1 ml/hr‐mmHg [1–0.0761/hr t] (P Bo ‐P Do )