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A Hemoperfusion Column Based on Activated Carbon Granules Coated with an Ultrathin Membrane of Cellulose Acetate
Author(s) -
Tijssen Johan,
Bantjes Adriaan,
Doorn Albert W. J.,
Feijen Jan,
Dijk Boudewijn,
Vonk Carel R.,
Dijkhuis Ido C.
Publication year - 1979
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1111/j.1525-1594.1979.tb03797.x
Subject(s) - hemoperfusion , activated carbon , coating , chemical engineering , chromatography , chemistry , cellulose , membrane , cellulose acetate , adsorption , materials science , organic chemistry , surgery , medicine , biochemistry , hemodialysis , engineering
A hemoperfusion system has been developed which makes use of activated carbon encapsulated with cellulose acetate. Studies have revealed that there are no stagnant flow regions in the column, there i? minimal particle release and the coating is 30 Å thick. The relationships between pore size, pore volume and surface area have been examined. Twenty‐five patients in grade IV coma have been treated with the column for treatment of drug overdose or agricultural chemical poisoning; the clinical course of one meprobamate‐poisoned patient is described in detail.