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Applications of the Redy® Sorbent System to Hemodialysis and Peritoneal Dialysis
Author(s) -
Blumenkrantz Michael J.,
Gordon Arthur,
Roberts Martin,
Lewin Andrew J.,
Peeker Edwin A.,
Moran John K.,
Coburn Jack W.,
Maxwell Morton H.
Publication year - 1979
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1111/j.1525-1594.1979.tb01054.x
Subject(s) - sorbent , peritoneal dialysis , hemodialysis , medicine , uremia , urea , adsorption , dialysis , intensive care medicine , chemistry , surgery , organic chemistry
The application of sorbent technology to the treatment of uremia has been limited by the inability to adsorb urea adequately. Conversion of urea to ammonium carbonate and adsorption by zirconium phosphate provides a practical means of removing urea. This combination, together with hydrated zirconium oxide and carbon, removes uremic waste products from dialysate. Over 1500 patients are undergoing maintenance hemodialysis with this system. The dialysate composition can be modified for the treatment of patients with acute renal failure. This sorbent system is now being used for the regeneration of peritoneal dialysate. Twenty patients have undergone a total of 90 dialyses, each of 4 to 24 hours duration. One home patient has been solely on this system for two months. The application of sorbent technology to peritoneal dialysis may be the most promising approach to a wearable dialysis system.