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Emergence of Multiresistant Methicillin‐Resistant S taphylococcus aureus in Two Patients with Atopic Dermatitis Requiring Linezolid Treatment
Author(s) -
Rosa Jaime S.,
Ross Lawrence A.,
Ong Peck Y.
Publication year - 2012
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/j.1525-1470.2012.01870.x
Subject(s) - medicine , methicillin resistant staphylococcus aureus , mupirocin , linezolid , clindamycin , atopic dermatitis , staphylococcus aureus , fusidic acid , trimethoprim , staphylococcal infections , antibiotics , dermatology , regimen , staphylococcal skin infections , microbiology and biotechnology , vancomycin , biology , bacteria , genetics
We report two patients with atopic dermatitis who developed methicillin‐resistant S taphylococcus aureus ( MRSA ) skin infections resistant to clindamycin and trimethoprim‐sulfamethoxazole requiring repeated linezolid treatment. For one patient and family members who received an aggressive regimen of staphylococcal decolonization, including intranasal mupirocin, dilute bleach baths, and bleach cleansing of household items and surfaces, subsequent culture results demonstrated methicillin‐susceptible S . aureus colonization and infection. These findings underscore the challenges presented by multiresistant MRSA infections in children with atopic dermatitis.