Premium
Asymmetric Crying Face in a Newborn with Isotretinoin Embryopathy
Author(s) -
Sarici Dilek,
Akin Mustafa Ali,
Kurtoglu Selim,
Uzum Kazim,
Kiraz Aslihan
Publication year - 2012
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/j.1525-1470.2012.01743.x
Subject(s) - isotretinoin , medicine , crying , retinoic acid , pregnancy , tretinoin , facial muscles , dermatology , anatomy , genetics , psychiatry , biology , acne , gene
We report a newborn with asymmetric crying face and other anomalies whose mother had taken isotretinoin during the first month of pregnancy. We hypothesize that asymmetric crying face is a finding of retinoic acid embryopathy and results from the intrauterine effects of retinoic acid on the development of the depressor anguli oris muscle or the mandibular branch of the facial nerve.