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Treatment of Hypergranulation Tissue with High Potency Topical Corticosteroids in Children
Author(s) -
McShane Diana B.,
Bellet Jane S.
Publication year - 2012
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/j.1525-1470.2012.01724.x
Subject(s) - medicine , granulation tissue , potency , angiogenesis , wound healing , dermatology , matrix metalloproteinase , topical steroid , surgery , complication , biochemistry , chemistry , in vitro
Hypergranulation is having more granulation tissue than needed to fill a wound defect. Some pediatric dermatologists and most dermatologic surgeons will encounter this complication during their careers. Associated factors include wound site, prolonged inflammation, an imbalance in matrix metalloproteinases, and excessive angiogenesis. Reported treatments have included silver nitrate, excision, laser ablation, and topical corticosteroids. Our case series supports the use of medium‐ to high‐potency topical corticosteroids in the treatment of hypergranulation tissue.