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Should Idiopathic Facial Aseptic Granuloma Be Considered Granulomatous Rosacea? Report of Three Pediatric Cases
Author(s) -
Neri Iria,
Raone Beatrice,
Dondi Arianna,
Misciali Cosimo,
Patrizi Annalisa
Publication year - 2012
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/j.1525-1470.2011.01689.x
Subject(s) - rosacea , medicine , folliculitis , nodule (geology) , granuloma , dermatology , etiology , histiocyte , granulomatous inflammation , pathology , granuloma formation , granulomatous disease , sarcoidosis , paleontology , acne , biology
Idiopathic facial aseptic granuloma (IFAG), or pyodermite froide du visage , is a skin disease reported only in children and characterized by painless red nodules usually located on the cheeks. Its etiology is still unclear, but some authors considered the possibility that IFAG might be included in the spectrum of granulomatous rosacea (GR). The histopathological features of IFAG and GR are quite similar, showing perifolliculitis, granulomas, folliculitis, and lymphocytes and plasmacells around epithelioid histiocytes. In the present article, we discuss three cases in which an association between a facial nodule, compatible with both IFAG and GR, and recurrent chalazia make us support the hypothesis that IFAG should be considered as GR.