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Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Associated with Azithromycin in Acute Epstein‐Barr Virus Infection
Author(s) -
BAUER KIMBERLY A.,
BRIMHALL ANGELA K.,
CHANG TIMOTHY T.
Publication year - 2011
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/j.1525-1470.2011.01558.x
Subject(s) - medicine , eosinophilia , azithromycin , intensive care unit , antibiotics , epstein–barr virus infection , drug , immunology , virus , dermatology , epstein–barr virus , intensive care medicine , pharmacology , microbiology and biotechnology , biology
We report the first pediatric case of drug reaction with eosinophilia and systemic symptoms associated with azithromycin use in the setting of acute Epstein‐Barr virus infection in an 8‐year‐old boy. Our patient presented with fever, cutaneous eruption, eosinophilia, and hypotension requiring intensive care unit admission. He was discharged in good condition without any long‐term sequelae. This case underscores the importance of timely and accurate diagnosis of acute viral infections and appropriate use of antibiotics as well as recognition of the clinical signs of drug reaction with eosinophilia and systemic symptoms.