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Fatal Leptomeningeal Melanoma in Neurocutaneous Melanosis
Author(s) -
Furtado Shireen,
Furtado Sunil V.,
Ghosal Nandita,
Hegde Alangar S.
Publication year - 2011
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/j.1525-1470.2011.01424.x
Subject(s) - medicine , melanosis , dermatology , lesion , melanoma , intracranial pressure , pathology , surgery , cancer research
We report an unusual occurrence of a primary dural‐based malignant melanoma in a 13‐year‐old boy with neurocutaneous melanosis. The lesion presented with rapid‐onset symptoms characterized by raised intracranial pressure and seizures, had an aggressive clinical course, and proved to be fatal despite two surgeries and adjuvant therapy. There should be a high index of suspicion for the occurrence of such a malignant leptomeningeal tumor in patients with congenital melanocytic nevi presenting with neurological symptoms of recent onset.