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Juvenile Xanthogranuloma in Monozygotic Twins
Author(s) -
TAN KIWEI,
AAN KOH MARK JEAN,
TAY YONGKWANG
Publication year - 2010
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/j.1525-1470.2010.01332.x
Subject(s) - juvenile xanthogranuloma , medicine , asymptomatic , etiology , monozygotic twin , genetic predisposition , trunk , juvenile , dermatology , pediatrics , pathology , genetics , biology , disease , ecology , histiocyte
Juvenile xanthogranuloma is usually a benign condition mainly seen in infants and children. It frequently presents as asymptomatic discrete papules on the head, trunk, and limbs. Extracutaneous manifestations, most commonly ocular, are rare but may be associated with significant morbidity. The etiology of juvenile xanthogranuloma is uncertain, although the occurrence in monozygotic twins may suggest genetic predisposition.