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Linear Childhood Discoid Lupus Erythematosus Following the Lines of Blaschko: Successfully Treated with Topical Tacrolimus
Author(s) -
KAWACHI YASUHIRO,
TAGUCHI SHIJIMA,
FUJISAWA YASUHIRO,
FURUTA JUNICHI,
NAKAMURA YASUHIRO,
ISHII YOSHIYUKI,
OTSUKA FUJIO
Publication year - 2010
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/j.1525-1470.2010.01249.x
Subject(s) - discoid lupus erythematosus , medicine , tacrolimus , dermatology , lupus erythematosus , systemic lupus erythematosus , pathology , immunology , disease , antibody , transplantation , surgery
The linear arrangement of discoid lupus erythematosus is uncommon. Here, we report a 6‐year‐old Japanese girl with linear discoid lupus erythematosus following the lines of Blaschko on her face and neck. Topical tacrolimus treatment improved the eruptions. The present case also indicated the important role of epidermal and dermal cells as well as immune cells in the pathogenesis of cutaneous lupus erythematodes.