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A Case of Erythema Multiforme Associated with Primary Epstein–Barr Virus Infection
Author(s) -
Nakai Hidetaka,
Sugata Ken,
Usui Chie,
Asano Yoshizo,
Yamakita Takashi,
Matsunaga Kayoko,
Mizokuchi Yoshikazu,
Katano Harutaka,
Iwatsuki Keiji,
Yoshikawa Tetsushi
Publication year - 2011
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/j.1525-1470.2010.01217.x
Subject(s) - erythema multiforme , medicine , primary (astronomy) , epstein–barr virus infection , epstein–barr virus , virology , dermatology , virus , erythema , physics , astronomy
We present a case of primary Epstein–Barr virus (EBV) infection with erythema multiforme. A 1‐year‐old Japanese boy presented with skin eruptions, including typical target lesions and a low‐grade fever. Just before the skin biopsy, 95 copies/μg DNA of EBV genome was detected in peripheral blood mononuclear cells, which subsequently increased to 6,834 copies/μg DNA. Skin tissue collected from the skin lesion showed the typical pathologic findings of erythema multiforme. EBV‐encoded small nuclear RNA signals were not detected in the skin tissue by in situ hybridization.