z-logo
Premium
Witkop Tooth and Nail Syndrome: A Report of Three Cases in a Family
Author(s) -
Memarpour Mahtab,
Shafiei Fereshteh
Publication year - 2010
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/j.1525-1470.2010.01198.x
Subject(s) - medicine , hypodontia , disfigurement , ectodermal dysplasia , dentistry , nail (fastener) , dermatology , orthodontics , surgery , materials science , metallurgy
  Witkop tooth and nail syndrome is a rare autosomal dominant ectodermal dysplasia manifested by hypodontia and nail dysplasia. Tooth shape may vary, and conical and narrow crowns are common. Mandibular incisors, second molars, and maxillary canines are the most frequently missing teeth. Nail dysplasia affects the fingernails and especially the toenails and is often more severe in childhood. Nails may be spoon‐shaped, ridged, slow‐growing, and easily broken. We examined an Eastern Mediterranean family in which three siblings (two girls, one boy) had this syndrome. The severity of finger and toenail anomalies varied. The children’s mother had no Witkop‐related abnormalities, but their father was reported to have dental and nail anomalies. Early intervention is recommended to manage orofacial disfigurement and avoid negative social consequences for these children.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here