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Agminated Spitz Nevi Arising on a Nevus Spilus after Chemotherapy
Author(s) -
AIDA KHALED,
MONIA KHARFI,
AHLEM SELLAMI,
DOMINIQUE HAMELTEILLAC,
BECIMA FAZAA,
SYLVIE FRAITAG,
RIDHA KAMOUN MOHAMED
Publication year - 2010
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/j.1525-1470.2010.01175.x
Subject(s) - medicine , dermatology , spitz nevus , nevus , chemotherapy , melanoma , rhabdomyosarcoma , pathology , surgery , sarcoma , cancer research
Abstract: Agminated Spitz nevus arising on a background of nevus spilus (NS) is a rare condition. We report here a further case in a child that is original because it is induced by chemotherapy. A 3‐year‐old boy presented 3 months after the onset of a chemotherapy for a vesico‐prostatic rhabdomyosarcoma, multiple pigmented papulo‐nodules located on the face, neck, chest wall, and the higher back. These lesions have arose on a pre‐existent large congenital histologically confirmed nevus spilus extending along the face, neck, the left shoulder and the left chest wall. Histological examination of three excised nodules led to the diagnosis of Spitz nevus. Our patient may have a high risk for melanoma since he has many criteria predisposing to this risk. Some of these criteria are related to NS but we should also take into account the chemotherapy induction and the high number of Spitz nevi.