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Pyoderma Gangrenosum‐like Lesions in Leukocyte Adhesion Deficiency I Treated with Intravenous Immunoglobulin
Author(s) -
Nord Kristin M.,
Pappert Amy S.,
Grossman Marc E.
Publication year - 2011
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/j.1525-1470.2010.01123.x
Subject(s) - medicine , pyoderma gangrenosum , antibiotics , antibody , surgery , immunoglobulin a , dermatology , adhesion , gastroenterology , immunoglobulin g , immunology , disease , microbiology and biotechnology , biology , chemistry , organic chemistry
A 31‐year‐old Caucasian male with leukocyte adhesion deficiency I and a 20‐year history of recurrent, painful cutaneous ulcerations on the extremities presented with fatigue and worsening pain in both legs. He had experienced minimal improvement in his leg ulcers from treatment with systemic steroids, numerous courses of systemic antibiotics, and brief trials of infliximab and mycophenolate mofetil. He was treated with monthly intravenous immunoglobulin infusions. Upon completion of six courses of intravenous immunoglobulin his ulcerations had nearly healed for the first time in a decade.