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A Randomized, Double‐Blind Study Comparing the Efficacy of Selenium Sulfide Shampoo 1% and Ciclopirox Shampoo 1% as Adjunctive Treatments for Tinea Capitis in Children
Author(s) -
Chen Catherine,
Koch Laine H.,
Dice James E.,
Dempsey Kimberly K.,
Moskowitz Alan B.,
BarnesEley Myra L.,
Hubbard Thomas W.,
Williams Judith V.
Publication year - 2010
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/j.1525-1470.2010.01093.x
Subject(s) - shampoo , tinea capitis , medicine , dermatology , scalp , adjunctive treatment , pathology
Our objective was to compare the efficacy of selenium sulfide shampoo 1% and ciclopirox shampoo 1% as adjunctive treatments for tinea capitis in children. Forty children aged 1–11 years with clinically diagnosed tinea capitis were randomized to receive selenium sulfide shampoo 1% or ciclopirox shampoo 1% twice a week as adjuncts to an 8‐week course of ultramicronized griseofulvin dosed at 10–12 mg/kg/day. At weeks 2, 4, and 8, subjects returned to the clinic for evaluation and scalp cultures. Subjects then returned for follow‐up visits 4 weeks after completing treatment. Overall, by 8 weeks, 30 of 33 (90.9%) treated children demonstrated mycological cure. Selenium sulfide shampoo 1% and ciclopirox shampoo 1% were equally effective as adjunctive treatments for tinea capitis in children in our study.