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Combination of 308‐nm Excimer Laser With Topical Pimecrolimus For the Treatment of Childhood Vitiligo
Author(s) -
HUILAN YANG,
XIAOYAN HUANG,
JIANYONG FAN,
ZONGRONG LIU
Publication year - 2009
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/j.1525-1470.2009.00914.x
Subject(s) - pimecrolimus , medicine , dermatology , vitiligo , excimer laser , excimer , randomized controlled trial , group b , calcineurin , surgery , laser , optics , physics , transplantation
Forty‐nine patients enrolled in a single‐blinded, randomized, comparing 308‐nm excimer laser therapy together with topical 1% pimecrolimus cream twice daily (group A) with excimer laser therapy twice per week (group B). Of 48 patients evaluated after 30 weeks of treatment, 71% of patients from group A achieved Grade 3 or 4 repigmentation compared with 50% in group B. Significant difference was found between group A and B at the end of 30 weeks of treatment (p = 0.001).