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Congenital Disseminated Pyogenic Granuloma
Author(s) -
Browning John C.,
Eldin Karen W.,
Kozakewich Harry P. W.,
Mulliken John B.,
Bree Alanna F.
Publication year - 2009
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/j.1525-1470.2008.00858.x
Subject(s) - pyogenic granuloma , medicine , staining , pathology , granuloma , lesion
In the past pyogenic granuloma (PG) in infancy has been easily confused clinically and histopathologically with infantile hemangioma (IH). In 2000 North and colleagues discovered that IH is immunopositive for GLUT‐1, a glucose transporter which is also expressed in placental capillaries (1). GLUT‐1 staining is negative in pyogenic granuloma. We report two newborns with congenital disseminated PG who were otherwise healthy. In both of these cases, negative GLUT‐1 staining supported the proper diagnosis.