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Systematized Contact Dermatitis and Montelukast in an Atopic Boy
Author(s) -
CastanedoTardan Mari Paz,
González Mercedes E.,
Connelly Elizabeth A.,
Giordano Kelly,
Jacob Sharon E.
Publication year - 2009
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/j.1525-1470.2008.00855.x
Subject(s) - montelukast , medicine , atopic dermatitis , dermatology , discontinuation , aspartame , contact dermatitis , allergy , surgery , asthma , immunology , food science , chemistry
Upon ingestion, the artificial sweetener, aspartame is metabolized to formaldehyde in the body and has been reportedly associated with systemic contact dermatitis in patients exquisitely sensitive to formaldehyde. We present a case of a 9‐year‐old Caucasian boy with a history of mild atopic dermatitis that experienced severe systematized dermatitis after being started on montelukast chewable tablets containing aspartame. Patch testing revealed multiple chemical sensitivities which included a positive reaction to formaldehyde. Notably, resolution of his systemic dermatitis only occurred with discontinuation of the montelukast chewables.