Premium
Adult T‐cell Leukemia/Lymphoma in an Adolescent Presenting with Skin Lesions
Author(s) -
Lucas Catherine T.,
Gillis Kendra J.,
Ness Jayne M.,
Hammers Yuki A.,
Crawford David F.,
Kelly David R.,
Theos Amy
Publication year - 2008
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/j.1525-1470.2008.00686.x
Subject(s) - medicine , lymphoma , leukemia , adult t cell leukemia/lymphoma , malignancy , t cell leukemia , chemotherapy , disease , immunology , pathology
Adult T‐cell leukemia/lymphoma is a T‐cell malignancy caused by the human T‐cell lymphotropic virus‐I. Adult T‐cell leukemia/lymphoma is primarily a disease of adults due to the long latency period between initial infection and development of leukemia. We present a case of acute adult T‐cell leukemia/lymphoma in an adolescent. Skin lesions had appeared 3 years earlier and were the initial sign of human T‐cell lymphotropic virus‐I infection and T‐cell malignancy. Her disease failed to respond to both intensive chemotherapy and antiviral therapy. Cutaneous lesions are sometimes the initial sign of adult T‐cell leukemia/lymphoma and early recognition is imperative.