Premium
Discoid Lupus Erythematosus in Children—A Retrospective Study of 34 Patients
Author(s) -
Sampaio Maria Carolina de Abreu,
De Oliveira Zilda Najjar Prado,
Machado Maria Cecília da Matta Rivitti,
Dos Reis Vítor Manoel Silva,
Vilela Maria Apparecida Constantino
Publication year - 2008
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/j.1525-1470.2008.00625.x
Subject(s) - medicine , discoid lupus erythematosus , lupus erythematosus , retrospective cohort study , dermatology , systemic lupus erythematosus , connective tissue disease , disease , autoimmune disease , immunology , antibody
Discoid lupus erythematosus is much less frequent and studied in children. We undertook a retrospective study of 34 children less than 16 years of age with this disease, seen over a period of 9 years. A female predominance of 2:1 was found. An association between discoid lupus erythematosus and systemic lupus erythematosus was observed in 23.5% of patients, a higher proportion compared to adult discoid lupus erythematosus. Disseminated lesions were much more frequent in patients with criteria for systemic lupus erythematosus (87.5% vs 34%), suggesting that it could be associated with a worse prognosis. Histologic findings were similar to those observed in adult discoid lupus erythematosus.