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Pigmentary Changes and Atopic Dermatitis in a Patient with Seckel Syndrome
Author(s) -
Brackeen Amy,
BabbTarbox Michelle,
Smith Jennifer
Publication year - 2007
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/j.1525-1470.2007.00334.x
Subject(s) - medicine , microcephaly , short stature , dermatology , atopic dermatitis , dwarfism , chin , pediatrics , osteopetrosis , nose , hypoplasia , anatomy , pathology , biochemistry , chemistry , gene
Seckel syndrome is a very rare form of primordial dwarfism characterized by antenatal and postnatal growth delay, proportionate extreme short stature, a prominent beak‐like nose, hypoplasia of the malar area, small chin, microcephaly, deformed ears lacking lobules, skeletal malformations, mental retardation, and developmental delay. This syndrome has been described with associated disorders of orthopedic, neurologic, hematologic, cardiac, and ocular systems; however, only a few reports mention dermatologic involvement. We describe a 5‐year‐old girl with classic Seckel syndrome who presented with moderately severe atopic dermatitis and diffuse hypopigmented macules and papules.