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Infantile Hemangiopericytoma – Case Report and Literature Review
Author(s) -
Futagami A.,
Aoki M.,
Iwakiri I.,
Hyakusoku H.,
Kawamoto M.,
Kawana S.
Publication year - 2006
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/j.1525-1470.2006.00263.x
Subject(s) - hemangiopericytoma , medicine , pathology , soft tissue , lesion , vascular tumor , immunohistochemistry , anatomy
Infantile hemangiopericytoma is a rare soft tissue neoplasm of pericytic origin and is almost always benign, despite its worrisome pathologic features. We describe a 2‐month‐old male infant with a soft tissue mass on his right thigh. Histologically, the lesion showed a characteristic hemangiopericytoma‐like vascular pattern, multilobulation, and moderate mitotic activity. These morphologic features were prediagnosed as infantile hemangiopericytoma. However, immunohistochemical and ultrastructural studies revealed a heterogeneous cellular composition, primarily pericytes and endothelial cells, similar to that observed in infantile myofibromatosis.