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Erythrokeratoderma Variabilis Successfully Treated with Topical Tazarotene
Author(s) -
Yoo Stephen,
Simzar Soheil,
Han Karen,
Takahashi Stefani,
Cotliar Ronald
Publication year - 2006
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/j.1525-1470.2006.00252.x
Subject(s) - tazarotene , genodermatosis , medicine , dermatology , tretinoin , erythema , retinoic acid , biochemistry , chemistry , psoriasis , gene
Erythrokeratoderma variabilis, also known as Mendes da Costa syndrome, is a genodermatosis belonging to the group of diseases known as the erythrokeratodermias. Erythrokeratoderma variabilis is characterized by two distinctive manifestations: well‐demarcated, variable, transient, figurate patches of erythema, and localized or generalized hyperkeratotic plaques. Treatments include topical retinoic acid, salicylic acid, and alpha‐hydroxy acid in petrolatum, but all have been reported to have limited, variable success rates. We report a child with erythrokeratoderma variabilis with no family history of this entity, successfully treated with topical tazarotene.