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Maturity‐Onset Diabetes of the Young with Necrobiosis Lipoidica and Granuloma Annulare
Author(s) -
Marchetti Federico,
Gerarduzzi Tania,
Longo Filippo,
Faleschini Elena,
Ventura Alessandro,
Tonini Giorgio
Publication year - 2006
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/j.1525-1470.2006.00227.x
Subject(s) - necrobiosis lipoidica , granuloma annulare , medicine , dermatology , diabetes mellitus , maturity (psychological) , endocrinology , psychology , developmental psychology
We describe a 12‐year‐old white girl with granuloma annulare localized to both ankles since she was five, necrobiosis lipoidica in the left pretibial region since she was ten, and a recent history of weakness, migraine, and weight loss. After initial evaluation, high fasting blood glucose levels and high hemoglobin A1c were found. The family history for non‐insulin‐dependent diabetes was suggestive of maturity‐onset diabetes of the young. Coexistence of necrobiosis lipoidica and granuloma annulare, together with a family history of non‐insulin‐dependent diabetes, the age of onset, and the absence of ketosis, are specific features making possible, a clinical diagnosis. Genetic confirmation may not be so easily accessible or necessary.