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Familial Nonmembranous Aplasia Cutis of the Scalp
Author(s) -
Baselga Eulalia,
Torrelo Antonio,
Drolet Beth A.,
Zambrano Antonio,
Alomar Agustin,
Esterly Nancy B.
Publication year - 2005
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/j.1525-1470.2005.22307.x
Subject(s) - aplasia cutis congenita , scalp , medicine , vertex (graph theory) , aplasia , skull , sagittal suture , dermatology , cutis , anatomy , combinatorics , graph , mathematics
Aplasia cutis of the scalp is often a sporadic condition, but familial occurrences with an autosomal dominant inheritance have been documented. Aplasia cutis of the scalp may be seen in two main clinical variants: oval‐shaped membranous aplasia cutis and irregular, larger defects. We report six families in whom more than one member has aplasia cutis of the scalp, all of them with large irregular defects located over the vertex or anterior to the vertex along the sagittal suture. We review previous reports of this entity with clinical pictures and note that in most instances, the defects are of the nonmembranous variant.