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Diffuse Normolipemic Plane Xanthoma in a 9‐year‐old Boy
Author(s) -
Hofmann Maja,
Zappel Kristina,
Trefzer Uwe,
Audring Heike,
AlbrechtNebe Helga,
Sterry Wolfram
Publication year - 2005
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/j.1525-1470.2005.22207.x
Subject(s) - xanthoma , medicine , cd68 , pathology , paraproteinemia , dermatology , giant cell , multiple myeloma , immunohistochemistry
Normolipemic plane xanthoma normally occurs in adults. We report the atypical instance of a 9‐year‐old boy who developed disseminated, flat, yellow‐brown plaques up to 2 to 3 cm without any complaints. The histology showed the hallmarks of xanthoma, including the presence of CD68+ foam cells and Touton giant cells. No systemic involvement or lipid disorders were evident. It is important to perform regular follow‐up of these patients because normolipemic plane xanthoma often precedes myeloproliferative disorders such as leukemia, paraproteinemia, or lymphoma.