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Successful Treatment of Localized Cutaneous Infection Caused by Mycobacterium scrofulaceum with Clarithromycin
Author(s) -
Jang HoSun,
Jo JuHyun,
Oh ChangKeun,
Kim MoonBum,
Lee JaeBong,
Chang Chulhun L.,
Kwon YooWook,
Kwon KyungSool
Publication year - 2005
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/j.1525-1470.2005.00120.x
Subject(s) - clarithromycin , dermis , medicine , biopsy , mycobacterium , lesion , nontuberculous mycobacteria , infiltration (hvac) , pathology , dermatology , microbiology and biotechnology , biology , tuberculosis , physics , thermodynamics , helicobacter pylori
Cutaneous infection arising from Mycobacterium scrofulaceum , a nontuberculous mycobacteria, has rarely been reported, and most of the reported infections were disseminated forms in patients with AIDS or other immunocompromising illness. We describe an occurrence of localized mycobacterial skin infection caused by M. scrofulaceum in a previously healthy child that manifested as a red nodule on the cheek. A biopsy specimen of the lesion demonstrated granulomatous infiltration in the dermis. M. scrofulaceum was isolated from culture of a tissue specimen. Polymerase chain reaction amplified specific fragments for M. scrofulaceum . The patient was treated successfully with clarithromycin as monotherapy for 6 months, leading to complete healing without recurrence during a follow‐up period of 2 years.