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Refractory Demodex Folliculitis in Five Children with Acute Lymphoblastic Leukemia
Author(s) -
Herron Mark D.,
O'Reilly Margretta A.,
Vanderhooft Sheryll L.
Publication year - 2005
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/j.1525-1470.2005.00103.x
Subject(s) - medicine , acute lymphocytic leukemia , dermatology , folliculitis , demodex , leukemia , metronidazole , refractory (planetary science) , immunology , lymphoblastic leukemia , antibiotics , microbiology and biotechnology , botany , physics , astrobiology , biology , mite
We report five children with acute lymphocytic leukemia on maintenance chemotherapy who had Demodex folliculitis. None experienced complete clearing when treated with permethrin 5% cream. Topical metronidazole helped to lessen the eruption in four, but did not provide full clearing. The one child who was treated with sodium sulfacetamide 10%, sulfur 5% formulation had resolution of the eruption. We suggest that treatment of Demodex folliculitis in children with acute lymphocytic leukemia is more difficult than is suggested in the literature. Newer sodium sulfacetamide/sulfur formulations should be considered when treating this condition, particularly in children with acute lymphocytic leukemia.