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Congenital Erythropoietic Porphyria Complicated by Squamous Cell Carcinoma
Author(s) -
Pandhi Deepika,
Suman Mansi,
Khuraeeta,
Reddy B. S. N.
Publication year - 2003
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/j.1525-1470.2003.20609.x
Subject(s) - medicine , basal cell , porphyria , sibling , disease , carcinoma , pathology , dermatology , developmental psychology , psychology
We report two sisters, ages 12 and 8 years, with the characteristic clinical and biochemical profile of congenital erythropoietic porphyria (CEP). The disease is inherited as an autosomal recessive. The elder sibling had squamous cell carcinoma arising from the stump of the amputated left arm with metastases to lymph nodes, adrenals, and bone. To our knowledge, this feature has not been described in the English language literature, making our patient the first documented report of CEP with squamous cell carcinoma.